We have over 60 years experience in... Peristaltic pumps, tube and hose pumps, sine pumps, liquid filling and OEM pumps
This site in other countries / regions:
You are here:
PureWeld XL - high performance TPE tubing
Continuous processing. How to manage the technical challenge
The technology used in the continuous process can pose a challenge. With this white paper a comparison of the peristaltic performance of three TPE tubing materials provides powerful insights into the effectiveness of different products.
Drug manufacturers are increasingly adopting continuous bioprocessing to manufacture biologics as efficiently as possible. This is being driven by a need to reduce production costs and prices of pharmaceutical products. Furthermore, the FDA has stated its support for the implementation of continuous bioprocessing. A key consequence of continuous bioprocessing is that single-use components and assemblies must maintain integrity for process cycle times of up to 90 days.
For peristaltic pump tubing, there is added complexity because of the loads placed on the tubing by the pump and the resultant dynamic wear on the tubing. A peristaltic tube must deliver confidence that it will not fail within the process cycle time and that it will deliver consistent flow rate over this time.
In view of this, Watson-Marlow Fluid Technology Group (WMFTG), fluid path solutions provider of peristaltic pumps and single-use components, outlines the results of a study which makes comparisons between the peristaltic life and pumping performance of PureWeld® XL TPE tubing and two leading industry alternatives.
The study reveals noteworthy results that affirm the need for drug manufacturers to consider the peristaltic life of all tubing products used in continuous bioprocessing.
This paper details that samples of WMFTG PureWeld XL tubing tubing were compared to two leading industry alternative SEBS TPE products to assess pumping performance over time and peristaltic life.
With the increasing integration of robust single-use technologies into cGMP bioprocess, there is a greater value placed on tubing and tubing assemblies within critical fluid path. Add to this the increasing adoption of continuous bioprocessing, and the resultant process cycle times of up to 90 days, it is essential that the peristaltic tubing used delivers long pumping life.
The increasing burden of materials validation within the bioprocessing industry has driven a desire to rationalise inventory and reduce the number of fluid contact materials. To meet this need, it is advantageous for the tubing used in the bioprocess assembly to deliver high performance in terms of peristaltic life.
There is growing acceptance of SEBS TPE materials due to their compatibility with sterile welding and sealing technologies, performance and levels of purity which meet the expectations of the industry and regulators. In addition, the worldwide shortage of silicone raw materials has brought an additional focus to the implementation of TPEs.
Find a pump
Include out of production models
Find tubing or hose
GORE STA-PURE PFL reinforced fluoroelastomer tubing
GORE STA-PURE PCS reinforced silicone tubing
PureWeld XL - high performance TPE tubing
Marprene long life process tubing
Neoprene industrial application tubing
Bulk Pumpsil, silicone or TPE tubing
Pumpsil - Platinum cured silicone tubing
Natural rubber (NR) Endurance
Buna N (NBR)
Bioprene - Thermoplastic tubing
APEX Buna N (NBR)
APEX Natural rubber
Watson-Marlow Tubing Validation
Sanitary LoadSure Fluid Path Kits
Customisable tubing products for OEMs
Pharmaline N and X
NBR for food
APEX NBR for food
[Missing text /modules/rightcolumn/finddistributor/country for en]
United States of America
Bosnia & Herzegovina
Central America and Caribbean
China, Peoples Repu...
Papua New Guinea
Trinidad and Tobago
United Arab Emirates
[Missing text /modules/rightcolumn/finddistributor/region for en]
KY West Tip
[Missing text /modules/rightcolumn/finddistributor/industry for en]
Food and beverage
Water and waste - Environmental
Print and packaging
Pulp and paper
Paint and pigments
[Missing text /modules/rightcolumn/finddistributor/brand for en]
For help or advice please contact us on:
Tel: +1 978 658 6168 and Toll free +1 800 282-8823
You can also send us an email or find your nearest distributor