Quantum: Redefining peristaltic technology for downstream bioprocessing

Quantum and ReNu SU Technology

Quantum and ReNu SU Technology

Quantum and ReNu SU Technology

Quantum and ReNu SU Technology

Quantum and ReNu SU Technology

Quantum and ReNu SU Technology

Contact Us

To order this product please contact us on:

Tel: +1 978 658 6168 and Toll free +1 800 282-8823

You can also send us an email or find your nearest distributor

 

Overview

Quantum: Redefining peristaltic technology for bioprocessing

Traditionally, peristaltic pumps have been the pump of choice in low pressure upstream processes including fermentation feed and media transfer. The gentle peristaltic pumping action guarantees low shear, high accuracy and zero cross contamination to uphold cell viability and corresponding high cell densities.

With this knowledge in mind, Watson-Marlow Fluid Technology Group designed and developed Quantum to redefine the use of peristaltic pump technology specifically for downstream bioprocessing. 

By adding Quantum’s unique and revolutionary capabilities to the established peristaltic pumping principle—matched with ReNu SU Technology—Quantum is clearly the most logical choice for downstream bioprocessing.

Trace pulsation at 3 bar 

The revolutionary performance provided by Quantum extends the frontiers of peristaltic technology, delivering up to 3 bar constant pressure with only trace pulsation of 0.12 bar throughout the flow range. 

Quantum 600 Graph one

Ultra-low shear  

Quantum matched with its patented ReNu SU Technology cartridge delivers ultra-low shear and accuracy at set speed throughout the cartridge life. The independent test data demonstrates how Quantum delivers low shear and higher process yields by comparing the mean diameter of fragile oil based emulsion particles as they pass through a pump. The particle breakdown is twice as much with the quaternary pump (grey line) as with Quantum (yellow line). Tests were conducted at 12 L/min and 14.5 psi (1 bar) pressure.

Quantum 600 Graph two
The data presented in the above two graphs was provided by an independent third-party source

 


Designed specifically for downstream  

Quantum delivers flow linearity throughout the pressure range. With a 4000:1 control ratio, operators can sustain constant transmembrane pressure in micro/ultrafiltration.

Quantum 600 Graph three

 

The Quantum pump

 

Quantum pump


Control

Pump drives
Manual control
Intuitive keypad and colour display
Choice of flowrate or speed display
Full calibration with choice of flow units
Remote control
Configurable Start/Stop, leak detector input (via contact closure or 5V TTL or 24V industrial logic)
Direction change and auto/manual toggle input (via contact closure or 5V TTL or 24V industrial logic)
Remote operation of MemoDose (foot/hand-switch or logic input)
Four configurable digital status outputs through 24V, 30W relays
Analogue speed control
Fully configurable inputs; 0-10V or 4-20mA
Analogue outputs; 0-10V, 4-20mA
Tacho frequency output; 0 to 1067 Hz, 0 to 400RPM
Security
3-level Security PIN lock

 

ReNu SU Technology

ReNu SU Cartridge Technology Quantum successfully combines application specific pump capabilities with single-use fluid path components such as the ground breaking ReNu SU Technology cartridge, the popular BioPure range of barbs, clamps, gaskets and high pressure braided hose. For the first time, this integrated approach allows a considerable reduction in cost and time of pump validation prior to being specified into single-use systems (SUS).

ReNu SU Technology cartridges are fully manufactured in ISO Class 7 cleanrooms and are suitable for gamma irradiation at up to 50kGy. 

ReNu SU Technology cartridges are supplied with an industry-leading validation guide. The guide includes a comprehensive set of biocompatibility data with material tests such as USP88, Class VI (in vivo) and USP87 (in vitro). Detailed extractable testing with a range of solvents in line with BPOG and BPSA guidelines has also been undertaken. The validation guide supports your validation process, reducing your overall time to market.

The secure and consistent positioning of the ReNu SU Technology cartridge in the pumphead—clamped firmly in place at its manifolds—guarantees a secure connection every time. Additionally each cartridge is supplied with a quick change kit comprising of clamps, gaskets and end caps all designed to keep the time it takes to replace a cartridge to a minimum.

Connection kits are also available consisting of braid reinforced silicone hose configured to customers’ requirements with BioBarb fittings. All components are manufactured in ISO Class 7 cleanrooms.

Single-use fluid path    

The synergy between peristaltic pumps and single-use pump systems cannot be overstated. The ReNu SU Technology cartridge slides effortlessly into position allowing for a change of fluid path in minutes whilst eliminating alignment errors. 

Validation

ReNu SU Technology and its raw materials have been tested under a range of pharmacopoeial and non-pharmacopoeial standards. These include:

Additional testing carried out includes extractables testing. For a summary of the validation/qualification testing that has been carried out on ReNu Su Technology, please see the ReNu SU Technology validation summary guide 

The full validation guide including additional information regarding test methods and actual test reports is available on request by submitting a validation request form

ReNu SU Technology, its raw materials and manufacturing process meets a number of regulatory compliance legislations. Specific statements relating to these compliances are available in the ReNu SU Technology compliance guide, this is available on request by submitting a validation request form

Brochure

Quantum brochure

Quantum pump brochure thumbnail (US)

Datasheet

Quantum datasheet

Manual

Quantum 600 (UK)

  • Contact Us

    To order this product please contact us on:

    Tel: +1 978 658 6168 and Toll free +1 800 282-8823

    You can also send us an email or find your nearest distributor